Product Name:Serlofenac Tablet

Composition:Serratiopeptidase 10 mg + Diclofenac 50 mg

Diclofenac is a non-steroidal anti-inflammatory drug (NSAID). It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

Serratiopeptidase is a proteolytic enzyme (protease) produced by enterobacterium Serratia sp.

>Indications :

• Acute muscle spasm
• Muscular cramp
• Low back pain
• Muscle spasm associated with spondylosis.
• Dental pain
• Osteoarthritis
• Rheumatoid arthritis

Pharmacokinets of Diclofenac:

• Absorption- It is rapidly and completely absorbed after oral administration
• Distribution- Widely distributed in the body as protein-bound form. It is highly protein-bound (>99.7%). Aceclofenac penetrates into the synovial fluid, where the concentrations reach approximately 60% of those in plasma.
• Metabolism- Metabolized into metabolites in the liver. Main metabolite is 4-hydroxyaceclofenac
• Excretion- It is excreted through urine mainly as conjugated hydroxymetabolites

Pharmacokinets of Serratiopeptidase:

• Orally absorbed. In the case of enteric coated tablet absorption take place in the intestine. After absorption it is directly enter in to the bloodstream. It is excreted via urine and bile.

Side effects:

• Nausea
• Diarrhea
• Rashes
• Vomiting
• Constipation
• Abdominal pain

Contraindications:

• Hypersensitivity to Paracetamol.
• Blood coagulation disorder

Special Precautions while taking:

• Blood disorder
• Stomach disorder
• Hypertension
• Hepatic failure

Storage:

Store it at room temperature (25˚C) & Protect from light & moisture.